Bos taurus Gene: MGAT4A | |||||
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Summary | |||||
InnateDB Gene | IDBG-630066.2 | ||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
Gene Symbol | MGAT4A | ||||
Gene Name | alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A | ||||
Synonyms | |||||
Species | Bos taurus | ||||
Ensembl Gene | ENSBTAG00000010388 | ||||
Encoded Proteins |
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
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Protein Structure | |||||
Useful resources | Stemformatics EHFPI ImmGen | ||||
Entrez Gene | |||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000071073:
This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||
Type | Protein coding | ||||
Genomic Location | Chromosome 11:3810019-3926273 | ||||
Strand | Reverse strand | ||||
Band | |||||
Transcripts |
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Interactions | |||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||
NETPATH | |||||
REACTOME |
N-Glycan antennae elongation pathway
Transport to the Golgi and subsequent modification pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
N-glycan antennae elongation in the medial/trans-Golgi pathway
Metabolism of proteins pathway
N-Glycan antennae elongation pathway
N-glycan antennae elongation in the medial/trans-Golgi pathway
Transport to the Golgi and subsequent modification pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Asparagine N-linked glycosylation pathway
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KEGG |
N-Glycan biosynthesis pathway
N-Glycan biosynthesis pathway
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INOH | |||||
PID NCI | |||||
Cross-References | |||||
SwissProt | |||||
TrEMBL | |||||
UniProt Splice Variant | |||||
Entrez Gene | |||||
UniGene | Bt.193 | ||||
RefSeq | NM_177520 | ||||
HUGO | |||||
OMIM | |||||
CCDS | |||||
HPRD | |||||
IMGT | |||||
EMBL | |||||
GenPept | |||||
RNA Seq Atlas | |||||