Bos taurus Gene: LIPT1
Summary
InnateDB Gene IDBG-630125.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LIPT1
Gene Name Lipoyltransferase 1, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003965
Encoded Proteins
Lipoyltransferase 1, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144182:
The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, the protein encoded by this gene transfers the lipoyl moiety to apoproteins. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 13. Read-through transcription also exists between this gene and the neighboring downstream mitochondrial ribosomal protein L30 (MRPL30) gene. [provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:4280893-4283779
Strand Forward strand
Band
Transcripts
ENSBTAT00000005171 ENSBTAP00000005171
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0006464 cellular protein modification process
GO:0009249 protein lipoylation
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Lipoic acid metabolism pathway
Lipoic acid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt O46419
TrEMBL
UniProt Splice Variant
Entrez Gene 286864
UniGene Bt.4519
RefSeq NM_174795 XM_005212289 XM_005212290
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB006441
GenPept BAA24354
RNA Seq Atlas 286864