Version 5.4
| Bos taurus Gene: RAPGEF5 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-630256.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | RAPGEF5 | ||||||||
| Gene Name | Uncharacterized protein | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000015539 | ||||||||
| Encoded Proteins |
Rap guanine nucleotide exchange factor (GEF) 5
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136237:
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 4:31017033-31222267 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | F1N3K6 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 519566 | ||||||||
| UniGene | Bt.94748 | ||||||||
| RefSeq | XM_002686711 XM_005198033 XM_005198034 XM_005198035 XM_005205289 XM_005205290 XM_005205291 XM_597790 | ||||||||
| HUGO | HGNC:16862 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02010185 DAAA02010186 DAAA02010187 DAAA02010188 DAAA02010189 DAAA02010190 DAAA02010191 DAAA02010192 DAAA02010193 DAAA02010194 DAAA02010195 DAAA02010196 DAAA02010197 DAAA02010198 DAAA02010199 DAAA02010200 DAAA02010201 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 519566 | ||||||||