Bos taurus Gene: GLO1
Summary
InnateDB Gene IDBG-630387.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GLO1
Gene Name lactoylglutathione lyase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012703
Encoded Proteins
lactoylglutathione lyase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124767:
The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. [provided by RefSeq, Jul 2008]
The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:12483468-12509232
Strand Reverse strand
Band
Transcripts
ENSBTAT00000016884 ENSBTAP00000016884
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004462 lactoylglutathione lyase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0008152 metabolic process
GO:0030316 osteoclast differentiation
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Pyruvate metabolism pathway
Pyruvate metabolism pathway
INOH
Pyruvate metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.7760
RefSeq NM_001083496 XM_005198778 XM_005208394
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas