Bos taurus Gene: IL17C | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-630421.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | IL17C | ||||||
Gene Name | Uncharacterized protein | ||||||
Synonyms | IL17C | ||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000047128 | ||||||
Encoded Proteins |
interleukin 17C
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
InnateDB Annotation from Orthologs | |||||||
Summary |
[Homo sapiens] IL17C is an essential autocrine cytokine that regulates innate epithelial immune responses.
[Mus musculus] Il17c is an essential autocrine cytokine that regulates innate epithelial immune responses. (Demonstrated in human)
[Mus musculus] Microbiota-driven Il17c induces Bcl2 and Bcl2l1 expression in intestinal epithelial cells in an autocrine manner to promote cell survival and tumorigenesis in both chemically induced and spontaneous intestinal tumor models.
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Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124391:
The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 18:13927668-13928674 | ||||||
Strand | Forward strand | ||||||
Band | |||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Cross-References | |||||||
SwissProt | |||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | |||||||
UniGene | |||||||
RefSeq | XM_002694857 XM_869815 | ||||||
HUGO | |||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | |||||||
GenPept | |||||||
RNA Seq Atlas | |||||||