Bos taurus Gene: PRLR | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-630451.3 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | PRLR | ||||||||||||||||||||||
Gene Name | prolactin receptor long form precursor | ||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||||
Ensembl Gene | ENSBTAG00000025035 | ||||||||||||||||||||||
Encoded Proteins |
prolactin receptor long form
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113494:
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 20:39073246-39137480 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | |||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH |
Prolactin pathway
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REACTOME |
Growth hormone receptor signaling pathway
Prolactin receptor signaling pathway
Nuclear signaling by ERBB4 pathway
Signaling by ERBB4 pathway
Cytokine Signaling in Immune system pathway
Signal Transduction pathway
Immune System pathway
Nuclear signaling by ERBB4 pathway
Prolactin receptor signaling pathway
Signaling by ERBB4 pathway
Cytokine Signaling in Immune system pathway
Immune System pathway
Growth hormone receptor signaling pathway
Signal Transduction pathway
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KEGG |
Neuroactive ligand-receptor interaction pathway
Cytokine-cytokine receptor interaction pathway
Jak-STAT signaling pathway pathway
Cytokine-cytokine receptor interaction pathway
Jak-STAT signaling pathway pathway
Neuroactive ligand-receptor interaction pathway
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INOH |
JAK STAT pathway and regulation pathway
JAK STAT pathway and regulation pathway
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PID NCI |
ErbB4 signaling events
Signaling events mediated by PTP1B
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | A0FKN7 C7T4W9 F1N4H8 Q6VLX1 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 281422 | ||||||||||||||||||||||
UniGene | |||||||||||||||||||||||
RefSeq | NM_001039726 XM_005221575 XM_005221576 XM_005221577 XM_005221578 | ||||||||||||||||||||||
HUGO | |||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | |||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | AY339393 DAAA02050660 DAAA02050661 EF028094 FJ901286 FJ901287 FJ901290 FJ901293 FJ901294 | ||||||||||||||||||||||
GenPept | AAR11218 ABK27616 ACU51004 ACU51005 ACU51008 ACU51011 ACU51012 | ||||||||||||||||||||||
RNA Seq Atlas | 281422 | ||||||||||||||||||||||