Version 5.4
Bos taurus Gene: PKIB
Summary
InnateDB Gene IDBG-630551.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PKIB
Gene Name cAMP-dependent protein kinase inhibitor beta
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004394
Encoded Proteins
IDBP-682011
protein kinase (cAMP-dependent, catalytic) inhibitor beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135549:
This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:28880110-29001337
Strand Reverse strand
Band
Transcripts
ENSBTAT00000005765 ENSBTAP00000005765
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004862 cAMP-dependent protein kinase inhibitor activity
Biological Process
GO:0006469 negative regulation of protein kinase activity
GO:0071901 negative regulation of protein serine/threonine kinase activity
GO:2000480 negative regulation of cAMP-dependent protein kinase activity
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000135549
View Gene Order
ENSMUSG00000019876
View Gene Order
Cross-References
SwissProt
TrEMBL Q0VCK2
UniProt Splice Variant
Entrez Gene 615798
UniGene Bt.46188
RefSeq NM_001114518 XM_005210730
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120128 DAAA02025656 DAAA02025657 DAAA02025658
GenPept AAI20129
RNA Seq Atlas 615798

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca