Version 5.4
Bos taurus Gene: C1QTNF3
Summary
InnateDB Gene IDBG-630554.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C1QTNF3
Gene Name complement C1q tumor necrosis factor-related protein 3 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017071
Encoded Proteins
IDBP-682014
complement C1q tumor necrosis factor-related protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 20739398
[Homo sapiens] C1q/TNF-related protein-3 (AMACR;C1QTNF3), a protein secreted by adipocytes (adipokine), inhibits three basic and common pro-inflammatory pathways involved in obesity and type 2 diabetes mellitus (adipo-inflammation) by acting as an endogenous LPS antagonist of the adipose tissue.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000082196:
Gene Information
Type Protein coding
Genomic Location Chromosome 20:39760050-39792323
Strand Forward strand
Band
Transcripts
ENSBTAT00000022698 ENSBTAP00000022698
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0042593 glucose homeostasis
GO:0045721 negative regulation of gluconeogenesis
GO:0051259 protein oligomerization
GO:0051897 positive regulation of protein kinase B signaling
GO:0070374 positive regulation of ERK1 and ERK2 cascade
Cellular Component
GO:0005576 extracellular region
GO:0005581 collagen trimer
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000082196
View Gene Order
ENSMUSG00000058914
View Gene Order
Cross-References
SwissProt
TrEMBL A7MB82
UniProt Splice Variant
Entrez Gene 531659
UniGene Bt.55778
RefSeq NM_001101138 XM_005221604
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151389 DAAA02050668
GenPept AAI51390
RNA Seq Atlas 531659

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca