Bos taurus Gene: POLR1D | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-630744.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | POLR1D | ||||||||||||
Gene Name | DNA-directed RNA polymerases I and III subunit RPAC2 | ||||||||||||
Synonyms | |||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000008642 | ||||||||||||
Encoded Proteins |
DNA-directed RNA polymerases I and III subunit RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186184:
The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 12:32523508-32556412 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | |||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
RNA Polymerase III Transcription pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
RNA Polymerase I Transcription Termination pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
Cytosolic sensors of pathogen-associated DNA pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
RNA Polymerase I Promoter Escape pathway
RNA Polymerase I Transcription pathway
Gene Expression pathway
Immune System pathway
RNA Polymerase I Chain Elongation pathway
RNA Polymerase III Transcription Initiation pathway
RNA Polymerase III Abortive And Retractive Initiation pathway
RNA Polymerase I Transcription Initiation pathway
Innate Immune System pathway
RNA Polymerase I Promoter Clearance pathway
RNA Polymerase III Chain Elongation pathway
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
RNA Polymerase III Transcription Termination pathway
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KEGG | |||||||||||||
INOH | |||||||||||||
PID NCI | |||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH |
TNFalpha pathway
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REACTOME |
RNA Polymerase III Abortive And Retractive Initiation pathway
RNA Polymerase III Transcription Termination pathway
RNA Polymerase III Chain Elongation pathway
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
RNA Polymerase I Transcription Termination pathway
RNA Polymerase I Chain Elongation pathway
RNA Polymerase I Promoter Escape pathway
RNA Polymerase I Transcription Initiation pathway
RNA Polymerase I Transcription pathway
RNA Polymerase III Transcription Initiation pathway
Innate Immune System pathway
Epigenetic regulation of gene expression pathway
RNA Polymerase I Promoter Clearance pathway
NoRC negatively regulates rRNA expression pathway
Immune System pathway
RNA Polymerase III Transcription pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Cytosolic sensors of pathogen-associated DNA pathway
Gene Expression pathway
Negative epigenetic regulation of rRNA expression pathway
Innate Immune System pathway
RNA Polymerase I Transcription pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Mus musculus biological processes pathway
NoRC negatively regulates rRNA expression pathway
RNA Polymerase III Transcription Initiation pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
RNA Polymerase I Transcription Termination pathway
NoRC negatively regulates rRNA expression pathway
Immune System pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
RNA Polymerase III Abortive And Retractive Initiation pathway
Epigenetic regulation of gene expression pathway
Cytosolic sensors of pathogen-associated DNA pathway
Gene Expression pathway
Negative epigenetic regulation of rRNA expression pathway
RNA Polymerase III Transcription Termination pathway
RNA Polymerase I Promoter Escape pathway
RNA Polymerase I Promoter Clearance pathway
RNA Polymerase I Chain Elongation pathway
RNA Polymerase III Transcription pathway
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
RNA Polymerase I Transcription Initiation pathway
RNA Polymerase III Chain Elongation pathway
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KEGG |
Pyrimidine metabolism pathway
Purine metabolism pathway
RNA polymerase pathway
Cytosolic DNA-sensing pathway pathway
Pyrimidine metabolism pathway
RNA polymerase pathway
Purine metabolism pathway
Cytosolic DNA-sensing pathway pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | Q2YDK5 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 539061 | ||||||||||||
UniGene | Bt.108007 Bt.23598 Bt.88134 | ||||||||||||
RefSeq | XM_005213789 NM_001076144 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | BC110181 DAAA02033160 | ||||||||||||
GenPept | AAI10182 | ||||||||||||
RNA Seq Atlas | 539061 | ||||||||||||