Version 5.4
Bos taurus Gene: ADAMTS7
Summary
InnateDB Gene IDBG-630860.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAMTS7
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001396
Encoded Proteins
IDBP-682392
ADAM metallopeptidase with thrombospondin type 1 motif, 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136378:
The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two C-terminal TS motifs. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:30835151-30897314
Strand Forward strand
Band
Transcripts
ENSBTAT00000038814 ENSBTAP00000038623
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0032331 negative regulation of chondrocyte differentiation
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071773 cellular response to BMP stimulus
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0009986 cell surface
GO:0031012 extracellular matrix
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000136378
View Gene Order
ENSMUSG00000032363
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22161
Post-translational protein modification pathway
REACT_200727
O-linked glycosylation pathway
REACT_17015
Metabolism of proteins pathway
REACT_200626
O-glycosylation of TSR domain-containing proteins pathway
REACT_211817
O-glycosylation of TSR domain-containing proteins pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_204003
O-linked glycosylation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1N2M2
UniProt Splice Variant
Entrez Gene
UniGene Bt.112101 Bt.112264 Bt.25220
RefSeq
HUGO HGNC:223
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02052417 DAAA02052418 DAAA02052419 DAAA02052420
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca