Bos taurus Gene: PYCR2
Summary
InnateDB Gene IDBG-631039.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PYCR2
Gene Name Pyrroline-5-carboxylate reductase 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005835
Encoded Proteins
Pyrroline-5-carboxylate reductase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143811:
This gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes the conversion of pyrroline-5-carboxylate to proline, which is the last step in proline biosynthesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:29695734-29699696
Strand Reverse strand
Band
Transcripts
ENSBTAT00000000047 ENSBTAP00000000047
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004735 pyrroline-5-carboxylate reductase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006561 proline biosynthetic process
GO:0008652 cellular amino acid biosynthetic process
GO:0055114 oxidation-reduction process
GO:0055129 L-proline biosynthetic process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Arginine and proline metabolism pathway
Arginine and proline metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q17QJ7
TrEMBL
UniProt Splice Variant
Entrez Gene 504987
UniGene Bt.7679
RefSeq NM_001075181
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC118324
GenPept AAI18325
RNA Seq Atlas 504987