Bos taurus Gene: CD40LG | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-631246.3 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | CD40LG | ||||||||||||||||||||||
Gene Name | CD40 ligand CD40 ligand, membrane form CD40 ligand, soluble form | ||||||||||||||||||||||
Synonyms | TNFSF5 | ||||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||||
Ensembl Gene | ENSBTAG00000017843 | ||||||||||||||||||||||
Encoded Proteins |
CD40 ligandCD40 ligand, membrane formCD40 ligand, soluble form
CD40 ligandCD40 ligand, membrane formCD40 ligand, soluble form
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102245:
The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome X:20249086-20260907 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | |||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Immune System pathway
Adaptive Immune System pathway
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
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KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Adaptive Immune System pathway
Immune System pathway
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Immune System pathway
Adaptive Immune System pathway
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KEGG |
Cell adhesion molecules (CAMs) pathway
Cytokine-cytokine receptor interaction pathway
T cell receptor signaling pathway pathway
Allograft rejection pathway
Autoimmune thyroid disease pathway
Systemic lupus erythematosus pathway
Primary immunodeficiency pathway
Asthma pathway
Intestinal immune network for IgA production pathway
Viral myocarditis pathway
Malaria pathway
Toxoplasmosis pathway
Cytokine-cytokine receptor interaction pathway
Cell adhesion molecules (CAMs) pathway
T cell receptor signaling pathway pathway
Asthma pathway
Allograft rejection pathway
Systemic lupus erythematosus pathway
Autoimmune thyroid disease pathway
Primary immunodeficiency pathway
Intestinal immune network for IgA production pathway
Viral myocarditis pathway
Malaria pathway
Toxoplasmosis pathway
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INOH |
JAK STAT pathway and regulation pathway
GPCR signaling pathway
JAK STAT pathway and regulation pathway
GPCR signaling pathway
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PID NCI |
CD40/CD40L signaling
Calcium signaling in the CD4+ TCR pathway
Beta2 integrin cell surface interactions
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
IL4-mediated signaling events
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | G3N339 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 282387 | ||||||||||||||||||||||
UniGene | Bt.49 | ||||||||||||||||||||||
RefSeq | NM_174624 | ||||||||||||||||||||||
HUGO | |||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | |||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | DAAA02067751 | ||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | 282387 | ||||||||||||||||||||||