Version 5.4
Bos taurus Gene: BT.44757
Summary
InnateDB Gene IDBG-631333.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.44757
Gene Name peroxisome assembly factor 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005532
Encoded Proteins
IDBP-682861
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124587:
This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases. This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity. Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:16583122-16597410
Strand Reverse strand
Band
Transcripts
ENSBTAT00000007275 ENSBTAP00000007275
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0032403 protein complex binding
GO:0042623 ATPase activity, coupled
Biological Process
GO:0006200 ATP catabolic process
GO:0006625 protein targeting to peroxisome
GO:0007031 peroxisome organization
GO:0016561 protein import into peroxisome matrix, translocation
GO:0050821 protein stabilization
Cellular Component
GO:0005737 cytoplasm
GO:0005777 peroxisome
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000124587
View Gene Order
ENSMUSG00000002763
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04146
Peroxisome pathway
mmu04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1B8F6
UniProt Splice Variant
Entrez Gene 781290
UniGene Bt.44757
RefSeq NM_001192947 XM_001249689 XM_005223463
HUGO HGNC:8859
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02055080
GenPept
RNA Seq Atlas 534944 781290

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca