Version 5.4
| Bos taurus Gene: RELN | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-631504.3 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | RELN | ||||||||||||
| Gene Name | Reelin | ||||||||||||
| Synonyms | |||||||||||||
| Species | Bos taurus | ||||||||||||
| Ensembl Gene | ENSBTAG00000003658 | ||||||||||||
| Encoded Proteins |
Reelin
Reelin
Reelin
Reelin
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| Protein Structure | |||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000189056:
This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 4:44892394-45289293 | ||||||||||||
| Strand | Reverse strand | ||||||||||||
| Band | |||||||||||||
| Transcripts |
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| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME | |||||||||||||
| KEGG |
ECM-receptor interaction pathway
Focal adhesion pathway
ECM-receptor interaction pathway
Focal adhesion pathway
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| INOH | |||||||||||||
| PID NCI |
Reelin signaling pathway
Lissencephaly gene (LIS1) in neuronal migration and development
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| Cross-References | |||||||||||||
| SwissProt | |||||||||||||
| TrEMBL | F1MJ99 | ||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 281450 | ||||||||||||
| UniGene | Bt.14565 Bt.61296 Bt.82217 | ||||||||||||
| RefSeq | NM_001206458 XM_005205336 | ||||||||||||
| HUGO | |||||||||||||
| OMIM | |||||||||||||
| CCDS | |||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| EMBL | DAAA02010510 DAAA02010511 DAAA02010512 DAAA02010513 DAAA02010514 DAAA02010515 DAAA02010516 | ||||||||||||
| GenPept | |||||||||||||
| RNA Seq Atlas | 281450 | ||||||||||||