Bos taurus Gene: MEF2D | |||||||||||||||||||||
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Summary | |||||||||||||||||||||
InnateDB Gene | IDBG-631559.3 | ||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
Gene Symbol | MEF2D | ||||||||||||||||||||
Gene Name | myocyte-specific enhancer factor 2D | ||||||||||||||||||||
Synonyms | |||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||
Ensembl Gene | ENSBTAG00000046545 | ||||||||||||||||||||
Encoded Proteins |
Myocyte enhancer factor 2D
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Protein Structure | |||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116604:
This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012] |
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Gene Information | |||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||
Genomic Location | Chromosome 3:14380072-14413740 | ||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||
Band | |||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||
NETPATH | |||||||||||||||||||||
REACTOME |
Circadian Clock pathway
CDO in myogenesis pathway
Organelle biogenesis and maintenance pathway
Developmental Biology pathway
Mitochondrial biogenesis pathway
Myogenesis pathway
Transcriptional activation of mitochondrial biogenesis pathway
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KEGG | |||||||||||||||||||||
INOH | |||||||||||||||||||||
PID NCI |
Signaling events mediated by HDAC Class III
Role of Calcineurin-dependent NFAT signaling in lymphocytes
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Cross-References | |||||||||||||||||||||
SwissProt | |||||||||||||||||||||
TrEMBL | F1CYZ1 F1D8T5 | ||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||
Entrez Gene | 100336730 | ||||||||||||||||||||
UniGene | Bt.97637 | ||||||||||||||||||||
RefSeq | NM_001205178 XM_005203602 XM_005203604 | ||||||||||||||||||||
HUGO | |||||||||||||||||||||
OMIM | |||||||||||||||||||||
CCDS | |||||||||||||||||||||
HPRD | |||||||||||||||||||||
IMGT | |||||||||||||||||||||
EMBL | DAAA02007129 DAAA02007130 DAAA02007131 DAAA02007132 DAAA02007133 DAAA02007134 HQ615718 HQ692911 HQ692912 | ||||||||||||||||||||
GenPept | ADX30638 ADX30639 ADX60068 | ||||||||||||||||||||
RNA Seq Atlas | 100336730 | ||||||||||||||||||||