InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CBLB

Summary

InnateDB Gene

IDBG-631651.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CBLB

Gene Name

E3 ubiquitin-protein ligase CBL-B

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000013057

Encoded Proteins

IDBP-683219

Cas-Br-M (murine) ecotropic retroviral transforming sequence b

IDBP-683221

Cas-Br-M (murine) ecotropic retroviral transforming sequence b

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114423:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:50659370-50880121

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000017358	ENSBTAP00000017358
ENSBTAT00000062945	ENSBTAP00000055296

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 59 interaction(s) predicted by orthology.

Predicted by orthology
Total	59 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001784	phosphotyrosine binding
GO:0004842	ubiquitin-protein transferase activity
GO:0004871	signal transducer activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0002669	positive regulation of T cell anergy
GO:0006955	immune response
GO:0007166	cell surface receptor signaling pathway
GO:0016567	protein ubiquitination
GO:0023051	regulation of signaling
GO:0035556	intracellular signal transduction
GO:0042110	T cell activation
GO:0045732	positive regulation of protein catabolic process
GO:0046642	negative regulation of alpha-beta T cell proliferation
GO:0050860	negative regulation of T cell receptor signaling pathway