Version 5.4
Bos taurus Gene: BORA
Summary
InnateDB Gene IDBG-631672.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BORA
Gene Name protein aurora borealis
Synonyms C12H13orf34
Species Bos taurus
Ensembl Gene ENSBTAG00000019886
Encoded Proteins
IDBP-683273
bora, aurora kinase A activator
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136122:
BORA is an activator of the protein kinase Aurora A (AURKA; MIM 603072), which is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis (Hutterer et al., 2006 [PubMed 16890155]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:47782115-47809879
Strand Forward strand
Band
Transcripts
ENSBTAT00000026496 ENSBTAP00000026496
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0007088 regulation of mitosis
GO:0032880 regulation of protein localization
GO:0060236 regulation of mitotic spindle organization
Cellular Component
GO:0072687 meiotic spindle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000136122
View Gene Order
ENSMUSG00000022070
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160315
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_115566
Cell Cycle pathway
REACT_2203
G2/M Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_21391
Mitotic G2-G2/M phases pathway
REACT_240530
G2/M Transition pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_188804
Cell Cycle pathway
REACT_246508
Mitotic G2-G2/M phases pathway
REACT_196635
Regulation of PLK1 Activity at G2/M Transition pathway
KEGG
INOH
PID NCI
plk1_pathway
PLK1 signaling events
Cross-References
SwissProt
TrEMBL F1N3C9
UniProt Splice Variant
Entrez Gene 514162
UniGene
RefSeq NM_001205779 XM_005213838
HUGO HGNC:24724
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02033485
GenPept
RNA Seq Atlas 514162

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca