Version 5.4
Bos taurus Gene: BT.65122
Summary
InnateDB Gene IDBG-631853.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.65122
Gene Name poly(ADP-ribose) glycohydrolase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000023018
Encoded Proteins
IDBP-683418
poly(ADP-ribose) glycohydrolase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000227345:
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. [provided by RefSeq, Jul 2008]
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 28:44283041-44397693
Strand Reverse strand
Band
Transcripts
ENSBTAT00000031269 ENSBTAP00000031225
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004649 poly(ADP-ribose) glycohydrolase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0016045 detection of bacterium
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
ENSMUSG00000021911
View Gene Order
ENSG00000227345
View Gene Order
Cross-References
SwissProt
TrEMBL F1MG95
UniProt Splice Variant
Entrez Gene 281377
UniGene Bt.106829 Bt.65122
RefSeq NM_174138 XM_005226555
HUGO HGNC:8605
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02062236
GenPept
RNA Seq Atlas 281377

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca