Version 5.4
Bos taurus Gene: NEK8
Summary
InnateDB Gene IDBG-632103.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEK8
Gene Name serine/threonine-protein kinase Nek8
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015535
Encoded Proteins
IDBP-683710
NIMA (never in mitosis gene a)- related kinase 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160602:
This gene encodes a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystic kidney disease in humans. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:20711306-20721692
Strand Forward strand
Band
Transcripts
ENSBTAT00000020643 ENSBTAP00000020643
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0009887 organ morphogenesis
GO:0035330 regulation of hippo signaling
Cellular Component
GO:0072372 primary cilium
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000160602
View Gene Order
ENSMUSG00000017405
View Gene Order
Cross-References
SwissProt
TrEMBL E1B827
UniProt Splice Variant
Entrez Gene 532332
UniGene Bt.42919
RefSeq NM_001192723
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02048605 DAAA02048606
GenPept
RNA Seq Atlas 532332

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca