Version 5.4
Bos taurus Gene: FLOT2
Summary
InnateDB Gene IDBG-632132.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FLOT2
Gene Name Flotillin-2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010073
Encoded Proteins
IDBP-683741
Flotillin-2
IDBP-683748
Flotillin-2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132589:
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:20810487-20815216
Strand Reverse strand
Band
Transcripts
ENSBTAT00000035265 ENSBTAP00000035143
ENSBTAT00000013288 ENSBTAP00000013288
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.
Predicted by orthology
Total 34 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0010629 negative regulation of gene expression
GO:0050821 protein stabilization
GO:0090002 establishment of protein localization to plasma membrane
GO:1902992 negative regulation of amyloid precursor protein catabolic process
Cellular Component
GO:0002080 acrosomal membrane
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0005901 caveola
GO:0016020 membrane
GO:0016600 flotillin complex
GO:0030139 endocytic vesicle
GO:0031982 vesicle
GO:0045121 membrane raft
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000132589
View Gene Order
ENSMUSG00000061981
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
hsa04910
Insulin signaling pathway pathway
mmu04910
Insulin signaling pathway pathway
INOH
PID NCI
p73pathway
p73 transcription factor network
tap63pathway
Validated transcriptional targets of TAp63 isoforms
Cross-References
SwissProt
TrEMBL F6Q9T8 Q58DF8
UniProt Splice Variant
Entrez Gene 615679
UniGene Bt.1315
RefSeq NM_001035466
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT021639 DAAA02048607 DAAA02048608
GenPept AAX46486
RNA Seq Atlas 615679

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca