Version 5.4
| Bos taurus Gene: SLC29A1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-632170.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | SLC29A1 | ||||||||
| Gene Name | equilibrative nucleoside transporter 1 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000015131 | ||||||||
| Encoded Proteins |
equilibrative nucleoside transporter 1
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112759:
This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 23:17845969-17856150 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane pathway
Transport of vitamins, nucleosides, and related molecules pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
SLC-mediated transmembrane transport pathway
Transport of vitamins, nucleosides, and related molecules pathway
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane pathway
Transmembrane transport of small molecules pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | Q0V8K9 Q3ZC83 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 510932 | ||||||||
| UniGene | Bt.49579 | ||||||||
| RefSeq | NM_001034398 XM_005223409 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC102846 BT026209 DAAA02055124 DAAA02055125 | ||||||||
| GenPept | AAI02847 ABG67048 | ||||||||
| RNA Seq Atlas | 510932 | ||||||||