Version 5.4
Bos taurus Gene: CNOT1
Summary
InnateDB Gene IDBG-632819.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNOT1
Gene Name CCR4-NOT transcription complex subunit 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020782
Encoded Proteins
IDBP-684652
CCR4-NOT transcription complex, subunit 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125107:
Gene Information
Type Protein coding
Genomic Location Chromosome 18:26390076-26447574
Strand Reverse strand
Band
Transcripts
ENSBTAT00000027695 ENSBTAP00000027695
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.
Predicted by orthology
Total 41 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004535 poly(A)-specific ribonuclease activity
GO:0005488 binding
GO:0005515 protein binding
GO:0030331 estrogen receptor binding
GO:0042974 retinoic acid receptor binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001829 trophectodermal cell differentiation
GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly
GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway
GO:0048387 negative regulation of retinoic acid receptor signaling pathway
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic
GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:2000036 regulation of stem cell maintenance
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005778 peroxisomal membrane
GO:0016020 membrane
GO:0030014 CCR4-NOT complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000125107
View Gene Order
ENSMUSG00000036550
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20514
Deadenylation of mRNA pathway
REACT_20639
Deadenylation-dependent mRNA decay pathway
REACT_71
Gene Expression pathway
REACT_244119
Deadenylation of mRNA pathway
REACT_233572
Gene Expression pathway
REACT_235784
Deadenylation-dependent mRNA decay pathway
KEGG
hsa03018
RNA degradation pathway
mmu03018
RNA degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.105056
RefSeq NM_001206039 XM_005218664 XM_005218665 XM_005218666 XM_005218667 XM_005218668
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca