InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PARVA

Summary

InnateDB Gene

IDBG-632993.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PARVA

Gene Name

alpha-parvin

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000000700

Encoded Proteins

IDBP-684664

alpha-parvin

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197702:
This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:40748739-40902329

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000000935

ENSBTAP00000000935

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding

Biological Process

GO:0002040	sprouting angiogenesis
GO:0003148	outflow tract septum morphogenesis
GO:0007155	cell adhesion
GO:0007163	establishment or maintenance of cell polarity
GO:0031532	actin cytoskeleton reorganization
GO:0034113	heterotypic cell-cell adhesion
GO:0034446	substrate adhesion-dependent cell spreading
GO:0060271	cilium morphogenesis
GO:0070252	actin-mediated cell contraction
GO:0071670	smooth muscle cell chemotaxis