Version 5.4
Bos taurus Gene: CGN
Summary
InnateDB Gene IDBG-633083.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CGN
Gene Name cingulin
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017564
Encoded Proteins
IDBP-684764
cingulin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143375:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:19290676-19309322
Strand Reverse strand
Band
Transcripts
ENSBTAT00000023352 ENSBTAP00000023352
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005515 protein binding
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005923 tight junction
GO:0016459 myosin complex
GO:0043296 apical junction complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000143375
View Gene Order
ENSMUSG00000068876
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_11
TCR pathway
REACTOME
REACT_120726
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) pathway
REACT_169107
SMAD4 MH2 Domain Mutants in Cancer pathway
REACT_169219
Loss of Function of SMAD4 in Cancer pathway
REACT_169398
Loss of Function of SMAD2/3 in Cancer pathway
REACT_169122
Signaling by TGF-beta Receptor Complex in Cancer pathway
REACT_169192
TGFBR2 MSI Frameshift Mutants in Cancer pathway
REACT_111102
Signal Transduction pathway
REACT_169165
SMAD2/3 MH2 Domain Mutants in Cancer pathway
REACT_169435
Loss of Function of TGFBR2 in Cancer pathway
REACT_169103
SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway
REACT_169263
TGFBR1 KD Mutants in Cancer pathway
REACT_169311
Loss of Function of TGFBR1 in Cancer pathway
REACT_169445
TGFBR1 LBD Mutants in Cancer pathway
REACT_169440
TGFBR2 Kinase Domain Mutants in Cancer pathway
REACT_116125
Disease pathway
REACT_6844
Signaling by TGF-beta Receptor Complex pathway
KEGG
hsa04530
Tight junction pathway
mmu04530
Tight junction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MYN2
UniProt Splice Variant
Entrez Gene 533725
UniGene Bt.11656
RefSeq NM_001192786 XM_005203910 XM_005203911 XM_005203912
HUGO HGNC:17429
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02007247
GenPept
RNA Seq Atlas 533725

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca