Version 5.4
Bos taurus Gene: BT.88183
Summary
InnateDB Gene IDBG-633155.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.88183
Gene Name tectonic-1 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009208
Encoded Proteins
IDBP-684844
tectonic family member 1
IDBP-684847
tectonic family member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204852:
This gene encodes a member of the tectonic family of secreted and transmembrane proteins. The orthologous gene in mouse is required for formation of most ventral cell types. It functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:56724729-56752196
Strand Forward strand
Band
Transcripts
ENSBTAT00000012137 ENSBTAP00000012137
ENSBTAT00000065505 ENSBTAP00000056056
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001841 neural tube formation
GO:0008589 regulation of smoothened signaling pathway
GO:0021523 somatic motor neuron differentiation
GO:0021537 telencephalon development
GO:0021904 dorsal/ventral neural tube patterning
GO:0021956 central nervous system interneuron axonogenesis
GO:0060271 cilium morphogenesis
Cellular Component
GO:0005615 extracellular space
GO:0016020 membrane
GO:0035869 ciliary transition zone
GO:0036038 TCTN-B9D complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000204852
View Gene Order
ENSMUSG00000038593
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.88183
RefSeq NM_001046056 XM_005217781 XM_005217782
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca