Version 5.4
Bos taurus Gene: ADCYAP1R1
Summary
InnateDB Gene IDBG-633373.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADCYAP1R1
Gene Name Pituitary adenylate cyclase-activating polypeptide type I receptor
Synonyms PACAPR
Species Bos taurus
Ensembl Gene ENSBTAG00000020247
Encoded Proteins
IDBP-685086
Pituitary adenylate cyclase-activating polypeptide type I receptor
IDBP-685088
Pituitary adenylate cyclase-activating polypeptide type I receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000078549:
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:65670543-65729276
Strand Reverse strand
Band
Transcripts
ENSBTAT00000026333 ENSBTAP00000026333
ENSBTAT00000063163 ENSBTAP00000055102
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0004999 vasoactive intestinal polypeptide receptor activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000078549
View Gene Order
ENSMUSG00000029778
View Gene Order
Pathways
NETPATH
REACTOME
REACT_224969
NGF-independant TRKA activation pathway
REACT_220607
Glucagon-type ligand receptors pathway
REACT_205369
Signaling by GPCR pathway
REACT_226916
Activation of TRKA receptors pathway
REACT_206547
G alpha (s) signalling events pathway
REACT_214353
Signal Transduction pathway
REACT_207949
NGF signalling via TRKA from the plasma membrane pathway
REACT_214436
GPCR downstream signaling pathway
REACT_220217
GPCR ligand binding pathway
REACT_207066
Signalling by NGF pathway
REACT_204109
Class B/2 (Secretin family receptors) pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11046
NGF-independant TRKA activation pathway
REACT_19327
G alpha (s) signalling events pathway
REACT_18377
Glucagon-type ligand receptors pathway
REACT_18372
Class B/2 (Secretin family receptors) pathway
REACT_11061
Signalling by NGF pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_12056
NGF signalling via TRKA from the plasma membrane pathway
REACT_21340
GPCR ligand binding pathway
REACT_11064
Activation of TRKA receptors pathway
REACT_242871
G alpha (s) signalling events pathway
REACT_231304
Glucagon-type ligand receptors pathway
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_250061
Class B/2 (Secretin family receptors) pathway
REACT_231468
GPCR ligand binding pathway
REACT_248921
Signalling by NGF pathway
REACT_237883
NGF signalling via TRKA from the plasma membrane pathway
REACT_188257
Signal Transduction pathway
REACT_209347
NGF-independant TRKA activation pathway
REACT_217410
Activation of TRKA receptors pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
mmu04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq XM_005205487 XM_005205488
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca