Version 5.4
| Bos taurus Gene: ATP6V0D1 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-633557.3 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | ATP6V0D1 | ||||||||||||
| Gene Name | V-type proton ATPase subunit d 1 | ||||||||||||
| Synonyms | ATP6D; ATP6DV | ||||||||||||
| Species | Bos taurus | ||||||||||||
| Ensembl Gene | ENSBTAG00000014553 | ||||||||||||
| Encoded Proteins |
V-type proton ATPase subunit d 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159720:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. [provided by RefSeq, Jul 2008] This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c\', c\'\', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 18:35165958-35205066 | ||||||||||||
| Strand | Reverse strand | ||||||||||||
| Band | |||||||||||||
| Transcripts |
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| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Transferrin endocytosis and recycling pathway
Phagosomal maturation (early endosomal stage) pathway
Iron uptake and transport pathway
Transmembrane transport of small molecules pathway
Latent infection of Homo sapiens with Mycobacterium tuberculosis pathway
Signal Transduction pathway
Signaling by Insulin receptor pathway
IRE1alpha activates chaperones pathway
Metabolism of proteins pathway
XBP1(S) activates chaperone genes pathway
Unfolded Protein Response (UPR) pathway
Insulin receptor recycling pathway
Disease pathway
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| KEGG | |||||||||||||
| INOH | |||||||||||||
| PID NCI | |||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Transferrin endocytosis and recycling pathway
Iron uptake and transport pathway
Insulin receptor recycling pathway
Signaling by Insulin receptor pathway
XBP1(S) activates chaperone genes pathway
IRE1alpha activates chaperones pathway
Phagosomal maturation (early endosomal stage) pathway
Transmembrane transport of small molecules pathway
Unfolded Protein Response (UPR) pathway
Signal Transduction pathway
Metabolism of proteins pathway
Latent infection of Homo sapiens with Mycobacterium tuberculosis pathway
Disease pathway
Disease pathway
Signaling by Insulin receptor pathway
Unfolded Protein Response (UPR) pathway
Transferrin endocytosis and recycling pathway
Phagosomal maturation (early endosomal stage) pathway
Latent infection of Homo sapiens with Mycobacterium tuberculosis pathway
Metabolism of proteins pathway
Iron uptake and transport pathway
IRE1alpha activates chaperones pathway
Transmembrane transport of small molecules pathway
XBP1(S) activates chaperone genes pathway
Insulin receptor recycling pathway
Signal Transduction pathway
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| KEGG |
Vibrio cholerae infection pathway
Epithelial cell signaling in Helicobacter pylori infection pathway
Oxidative phosphorylation pathway
Lysosome pathway
Collecting duct acid secretion pathway
Phagosome pathway
Oxidative phosphorylation pathway
Lysosome pathway
Phagosome pathway
Collecting duct acid secretion pathway
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| INOH | |||||||||||||
| PID NCI | |||||||||||||
| Cross-References | |||||||||||||
| SwissProt | P61420 | ||||||||||||
| TrEMBL | |||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 282148 | ||||||||||||
| UniGene | Bt.1575 | ||||||||||||
| RefSeq | NM_174505 | ||||||||||||
| HUGO | |||||||||||||
| OMIM | |||||||||||||
| CCDS | |||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| EMBL | BC102305 J04204 | ||||||||||||
| GenPept | AAA64520 AAI02306 | ||||||||||||
| RNA Seq Atlas | 282148 | ||||||||||||