Bos taurus Gene: BT.80870
Summary
InnateDB Gene IDBG-633584.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.80870
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016991
Encoded Proteins
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125266:
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:86242384-86263272
Strand Reverse strand
Band
Transcripts
ENSBTAT00000035350 ENSBTAP00000035226
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0046875 ephrin receptor binding
Biological Process
GO:0001945 lymph vessel development
GO:0002042 cell migration involved in sprouting angiogenesis
GO:0007155 cell adhesion
GO:0007411 axon guidance
GO:0009887 organ morphogenesis
GO:0010839 negative regulation of keratinocyte proliferation
GO:0016477 cell migration
GO:0048013 ephrin receptor signaling pathway
GO:0048514 blood vessel morphogenesis
GO:0050920 regulation of chemotaxis
GO:2000727 positive regulation of cardiac muscle cell differentiation
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
EGFR1 pathway
REACTOME
Developmental Biology pathway
EPHB-mediated forward signaling pathway
Axon guidance pathway
Ephrin signaling pathway
EPH-ephrin mediated repulsion of cells pathway
EPH-Ephrin signaling pathway
EPH-ephrin mediated repulsion of cells pathway
EPH-Ephrin signaling pathway
EPHB-mediated forward signaling pathway
Axon guidance pathway
Developmental Biology pathway
Ephrin signaling pathway
KEGG
Axon guidance pathway
Axon guidance pathway
INOH
PID NCI
EPHB forward signaling
Ephrin B reverse signaling
EphrinB-EPHB pathway
Cross-References
SwissProt
TrEMBL F1N0M5
UniProt Splice Variant
Entrez Gene 100139818
UniGene
RefSeq
HUGO HGNC:3227
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02034841
GenPept
RNA Seq Atlas 100139818