Version 5.4
Bos taurus Gene: APOD
Summary
InnateDB Gene IDBG-634170.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APOD
Gene Name apolipoprotein D precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000023600
Encoded Proteins
IDBP-685931
apolipoprotein D precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000189058:
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:72670963-72684269
Strand Forward strand
Band
Transcripts
ENSBTAT00000046493 ENSBTAP00000043789
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0015485 cholesterol binding
GO:0036094 small molecule binding
Biological Process
GO:0000302 response to reactive oxygen species
GO:0006006 glucose metabolic process
GO:0006629 lipid metabolic process
GO:0006810 transport
GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0042308 negative regulation of protein import into nucleus
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0051895 negative regulation of focal adhesion assembly
GO:0060588 negative regulation of lipoprotein lipid oxidation
GO:0071638 negative regulation of monocyte chemotactic protein-1 production
GO:1900016 negative regulation of cytokine production involved in inflammatory response
GO:2000098 negative regulation of smooth muscle cell-matrix adhesion
GO:2000405 negative regulation of T cell migration
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005622 intracellular
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000189058
View Gene Order
ENSMUSG00000022548
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_23892
Transport of fatty acids pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_267716
Orphan transporters pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MS32
UniProt Splice Variant
Entrez Gene 613972
UniGene
RefSeq NM_001076301 XM_005201541
HUGO HGNC:612
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02001718
GenPept
RNA Seq Atlas 613972

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca