Bos taurus Gene: ACADVL | |||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||||||||||
InnateDB Gene | IDBG-634579.3 | ||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
Gene Symbol | ACADVL | ||||||||||||||||||||
Gene Name | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | ||||||||||||||||||||
Synonyms | |||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||
Ensembl Gene | ENSBTAG00000003072 | ||||||||||||||||||||
Encoded Proteins |
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
|
||||||||||||||||||||
Protein Structure | |||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000072778:
The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
||||||||||||||||||||
Gene Information | |||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||
Genomic Location | Chromosome 19:27568181-27573378 | ||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||
Band | |||||||||||||||||||||
Transcripts |
|
||||||||||||||||||||
Interactions | |||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
|
||||||||||||||||||||
Gene Ontology | |||||||||||||||||||||
Molecular Function |
|
||||||||||||||||||||
Biological Process |
|
||||||||||||||||||||
Cellular Component |
|
||||||||||||||||||||
Orthologs | |||||||||||||||||||||
Species
Homo sapiens
Mus musculus
|
Gene ID
Gene Order
|
||||||||||||||||||||
Pathways | |||||||||||||||||||||
NETPATH | |||||||||||||||||||||
REACTOME |
Mitochondrial Fatty Acid Beta-Oxidation pathway
IRE1alpha activates chaperones pathway
Beta oxidation of palmitoyl-CoA to myristoyl-CoA pathway
Metabolism of proteins pathway
Metabolism of lipids and lipoproteins pathway
XBP1(S) activates chaperone genes pathway
Metabolism pathway
Unfolded Protein Response (UPR) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
mitochondrial fatty acid beta-oxidation of saturated fatty acids pathway
|
||||||||||||||||||||
KEGG | |||||||||||||||||||||
INOH | |||||||||||||||||||||
PID NCI | |||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||
NETPATH | |||||||||||||||||||||
REACTOME |
XBP1(S) activates chaperone genes pathway
IRE1alpha activates chaperones pathway
Beta oxidation of palmitoyl-CoA to myristoyl-CoA pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Unfolded Protein Response (UPR) pathway
Metabolism of lipids and lipoproteins pathway
Mitochondrial Fatty Acid Beta-Oxidation pathway
Metabolism of proteins pathway
mitochondrial fatty acid beta-oxidation of saturated fatty acids pathway
Metabolism pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Mitochondrial Fatty Acid Beta-Oxidation pathway
Unfolded Protein Response (UPR) pathway
Metabolism pathway
Metabolism of proteins pathway
Metabolism of lipids and lipoproteins pathway
IRE1alpha activates chaperones pathway
mitochondrial fatty acid beta-oxidation of saturated fatty acids pathway
XBP1(S) activates chaperone genes pathway
Beta oxidation of palmitoyl-CoA to myristoyl-CoA pathway
|
||||||||||||||||||||
KEGG |
Fatty acid degradation pathway
Fatty acid degradation pathway
|
||||||||||||||||||||
INOH | |||||||||||||||||||||
PID NCI |
FOXA2 and FOXA3 transcription factor networks
|
||||||||||||||||||||
Cross-References | |||||||||||||||||||||
SwissProt | P48818 | ||||||||||||||||||||
TrEMBL | |||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||
Entrez Gene | 282130 | ||||||||||||||||||||
UniGene | Bt.48920 | ||||||||||||||||||||
RefSeq | NM_174494 XM_005220188 | ||||||||||||||||||||
HUGO | |||||||||||||||||||||
OMIM | |||||||||||||||||||||
CCDS | |||||||||||||||||||||
HPRD | |||||||||||||||||||||
IMGT | |||||||||||||||||||||
EMBL | BC103104 BT030546 U30817 | ||||||||||||||||||||
GenPept | AAA74051 AAI03105 ABQ12986 | ||||||||||||||||||||
RNA Seq Atlas | 282130 | ||||||||||||||||||||