Bos taurus Gene: IGF2BP2
Summary
InnateDB Gene IDBG-634762.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IGF2BP2
Gene Name insulin-like growth factor 2 mRNA-binding protein 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007666
Encoded Proteins
insulin-like growth factor 2 mRNA binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000073792:
This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four KH domains and two RRM domains. It functions by binding to the 5\' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms. [provided by RefSeq, May 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:81992398-82161528
Strand Forward strand
Band
Transcripts
ENSBTAT00000036032 ENSBTAP00000035897
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
GO:0048027 mRNA 5'-UTR binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA pathway
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BFI4
UniProt Splice Variant
Entrez Gene 519028
UniGene Bt.33805
RefSeq NM_001192504 XM_005201479 XM_005201480
HUGO HGNC:28867
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02001852 DAAA02001853 DAAA02001854 DAAA02001855 DAAA02001856
GenPept
RNA Seq Atlas 519028