InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: RGS17

Summary

InnateDB Gene

IDBG-634988.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RGS17

Gene Name

regulator of G-protein signaling 17

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000009277

Encoded Proteins

IDBP-686785

regulator of G-protein signaling 17

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000091844:
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:91105315-91135769

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000012221

ENSBTAP00000012221

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005096	GTPase activator activity

Biological Process

GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
GO:0038032	termination of G-protein coupled receptor signaling pathway
GO:0043547	positive regulation of GTPase activity