Bos taurus Gene: SHBG | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-635125.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | SHBG | ||||||
Gene Name | sex hormone-binding globulin precursor | ||||||
Synonyms | |||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000004226 | ||||||
Encoded Proteins |
sex hormone-binding globulin
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129214:
This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein binds each steroid molecule as a dimer formed from identical or nearly identical monomers. The use of alternate promoters and alternatively spliced transcripts have been described. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009] This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 19:27955573-27960099 | ||||||
Strand | Forward strand | ||||||
Band | |||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME | |||||||
KEGG | |||||||
INOH | |||||||
PID NCI |
Nongenotropic Androgen signaling
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Cross-References | |||||||
SwissProt | |||||||
TrEMBL | A5PKC2 Q6T181 Q6T182 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | 404182 | ||||||
UniGene | Bt.60925 | ||||||
RefSeq | NM_001098858 XM_005220313 XM_005220314 XM_005220315 XM_005220316 | ||||||
HUGO | |||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | AY443491 AY443492 BC142435 DAAA02048796 | ||||||
GenPept | AAI42436 AAR17085 AAR17086 | ||||||
RNA Seq Atlas | 404182 | ||||||