Bos taurus Gene: TNFRSF4 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-635323.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | TNFRSF4 | ||||||||||||
Gene Name | tumor necrosis factor receptor superfamily member 4 precursor | ||||||||||||
Synonyms | |||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000015635 | ||||||||||||
Encoded Proteins |
tumor necrosis factor receptor superfamily member 4
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186827:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 16:52484468-52487309 | ||||||||||||
Strand | Forward strand | ||||||||||||
Band | |||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME | |||||||||||||
KEGG |
Cytokine-cytokine receptor interaction pathway
Cytokine-cytokine receptor interaction pathway
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INOH | |||||||||||||
PID NCI |
Downstream signaling in naïve CD8+ T cells
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Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | A5PJH6 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 528782 | ||||||||||||
UniGene | Bt.62153 | ||||||||||||
RefSeq | NM_001099043 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | BC142115 DAAA02043240 | ||||||||||||
GenPept | AAI42116 | ||||||||||||
RNA Seq Atlas | 528782 | ||||||||||||