Version 5.4
| Bos taurus Gene: CD22 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Gene | IDBG-635610.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | CD22 | ||||||||
| Gene Name | Uncharacterized protein | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000011887 | ||||||||
| Encoded Proteins |
CD22 molecule
|
||||||||
| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| InnateDB Annotation from Orthologs | |||||||||
| Summary |
[Homo sapiens] CD22 (Siglec-2), like other sialic acid-binding immunoglobulin-like lectins (siglecs), is predominately expressed on immune cells. CD22 exhibits hallmarks of clathrin-mediated endocytosis and traffics to recycling compartment, reflecting its role in cell signalling and innate immunity.
[Homo sapiens] CD22 expression and function are differentially regulated in B-1 and conventional B-2 cells, which are implicated in innate and adaptive immunity, respectively.
|
||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000012124:
|
||||||||
| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 18:46228132-46239044 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
|
||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Orthologs | |||||||||
|
Species
Homo sapiens
Mus musculus
|
Gene ID
Gene Order
|
||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
BCR pathway
|
||||||||
| REACTOME | |||||||||
| KEGG |
Hematopoietic cell lineage pathway
Cell adhesion molecules (CAMs) pathway
B cell receptor signaling pathway pathway
Cell adhesion molecules (CAMs) pathway
Hematopoietic cell lineage pathway
B cell receptor signaling pathway pathway
|
||||||||
| INOH | |||||||||
| PID NCI |
BCR signaling pathway
|
||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Bt.109630 Bt.110916 | ||||||||
| RefSeq | XM_002695015 XM_002701839 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||