Version 5.4
| Bos taurus Gene: PPP3R1 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-635671.3 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | PPP3R1 | ||||||||||
| Gene Name | Calcineurin subunit B type 1 | ||||||||||
| Synonyms | |||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Gene | ENSBTAG00000010619 | ||||||||||
| Encoded Proteins |
Calcineurin subunit B type 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| InnateDB Annotation from Orthologs | |||||||||||
| Summary |
[Mus musculus] Ppp3r1 plays an important role in activation of peritoneal macrophages. Ppp3r1 induces Tnfsf10 (TRAIL) gene expression in peritoneal macrophages in an Itgam-dependent manner.
[Homo sapiens] PPP3R1 plays an important role in activation of peritoneal macrophages. PPP3R1 induces TNFSF10 (TRAIL) gene expression in peritoneal macrophages in an ITGAM-dependent manner. (Demonstrated in mice)
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| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000221823:
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 11:66582636-66642276 | ||||||||||
| Strand | Reverse strand | ||||||||||
| Band | |||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Mus musculus
Homo sapiens
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Gene ID
Gene Order
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Signaling by Wnt pathway
Signaling by GPCR pathway
DARPP-32 events pathway
Activation of BH3-only proteins pathway
Immune System pathway
FCERI mediated Ca+2 mobilization pathway
Ca2+ pathway pathway
Signal Transduction pathway
beta-catenin independent WNT signaling pathway
Intrinsic Pathway for Apoptosis pathway
Activation of BAD and translocation to mitochondria pathway
Opioid Signalling pathway
Innate Immune System pathway
Fc epsilon receptor (FCERI) signaling pathway
Apoptosis pathway
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| KEGG | |||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Innate Immune System pathway
Apoptosis pathway
Signaling by Wnt pathway
Signaling by GPCR pathway
DARPP-32 events pathway
beta-catenin independent WNT signaling pathway
Immune System pathway
Activation of BAD and translocation to mitochondria pathway
Fc epsilon receptor (FCERI) signaling pathway
Ca2+ pathway pathway
FCERI mediated Ca+2 mobilization pathway
Activation of BH3-only proteins pathway
Opioid Signalling pathway
Signal Transduction pathway
Intrinsic Pathway for Apoptosis pathway
DARPP-32 events pathway
Opioid Signalling pathway
Activation of BAD and translocation to mitochondria pathway
Ca2+ pathway pathway
beta-catenin independent WNT signaling pathway
Signaling by Wnt pathway
Signaling by GPCR pathway
Innate Immune System pathway
Fc epsilon receptor (FCERI) signaling pathway
Apoptosis pathway
Signal Transduction pathway
Activation of BH3-only proteins pathway
Immune System pathway
Intrinsic Pathway for Apoptosis pathway
FCERI mediated Ca+2 mobilization pathway
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| KEGG |
Axon guidance pathway
VEGF signaling pathway pathway
Calcium signaling pathway pathway
Alzheimer's disease pathway
T cell receptor signaling pathway pathway
Wnt signaling pathway pathway
Natural killer cell mediated cytotoxicity pathway
MAPK signaling pathway pathway
Long-term potentiation pathway
Apoptosis pathway
B cell receptor signaling pathway pathway
Amyotrophic lateral sclerosis (ALS) pathway
Oocyte meiosis pathway
Osteoclast differentiation pathway
VEGF signaling pathway pathway
Wnt signaling pathway pathway
Apoptosis pathway
MAPK signaling pathway pathway
Axon guidance pathway
Long-term potentiation pathway
Alzheimer's disease pathway
B cell receptor signaling pathway pathway
T cell receptor signaling pathway pathway
Natural killer cell mediated cytotoxicity pathway
Calcium signaling pathway pathway
Amyotrophic lateral sclerosis (ALS) pathway
Oocyte meiosis pathway
Osteoclast differentiation pathway
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| INOH |
CD4 T cell receptor signaling pathway
CD4 T cell receptor signaling pathway
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| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | P63099 | ||||||||||
| TrEMBL | A9ZTJ9 | ||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 282321 | ||||||||||
| UniGene | |||||||||||
| RefSeq | NM_174583 | ||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | AB375794 X71666 | ||||||||||
| GenPept | BAF99032 CAA50659 | ||||||||||
| RNA Seq Atlas | 282321 | ||||||||||