Bos taurus Gene: GAPDHS
Summary
InnateDB Gene IDBG-635698.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GAPDHS
Gene Name Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015917
Encoded Proteins
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105679:
This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:46385387-46394267
Strand Forward strand
Band
Transcripts
ENSBTAT00000021166 ENSBTAP00000021166
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding
Biological Process
GO:0006006 glucose metabolic process
GO:0006096 glycolytic process
GO:0030317 sperm motility
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005929 cilium
GO:0031514 motile cilium
GO:0035686 sperm fibrous sheath
GO:0097228 sperm principal piece
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Metabolism of carbohydrates pathway
Myoclonic epilepsy of Lafora pathway
Gluconeogenesis pathway
Glycogen storage diseases pathway
Glucose metabolism pathway
Metabolism pathway
Glycolysis pathway
Disease pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Glycolysis pathway
Gluconeogenesis pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Metabolism pathway
Disease pathway
Glucose metabolism pathway
Glycogen storage diseases pathway
Disease pathway
Glycolysis pathway
Glucose metabolism pathway
Metabolism pathway
Gluconeogenesis pathway
Glycogen storage diseases pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
KEGG
Glycolysis / Gluconeogenesis pathway
Glycolysis / Gluconeogenesis pathway
INOH
Glycolysis Gluconeogenesis pathway
PID NCI
Cross-References
SwissProt Q2KJE5
TrEMBL
UniProt Splice Variant
Entrez Gene 532231
UniGene Bt.91447
RefSeq NM_001040552 XM_005218971 XM_005218972
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105381
GenPept AAI05382
RNA Seq Atlas 532231