Version 5.4
Bos taurus Gene: CD83
Summary
InnateDB Gene IDBG-636028.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD83
Gene Name CD83 antigen precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000031430
Encoded Proteins
IDBP-687919
CD83 antigen
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112149:
The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:42335199-42354922
Strand Reverse strand
Band
Transcripts
ENSBTAT00000044544 ENSBTAP00000042033
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0014070 response to organic cyclic compound
GO:0032713 negative regulation of interleukin-4 production
GO:0032733 positive regulation of interleukin-10 production
GO:0032743 positive regulation of interleukin-2 production
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation
Cellular Component
GO:0009897 external side of plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000112149
View Gene Order
ENSMUSG00000015396
View Gene Order
Cross-References
SwissProt
TrEMBL Q2KHW2
UniProt Splice Variant
Entrez Gene 617034
UniGene Bt.64711 Bt.68747
RefSeq NM_001046590 XM_005223786
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112861 DAAA02055676
GenPept AAI12862
RNA Seq Atlas 617034

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca