Version 5.4
| Bos taurus Gene: VCAM1 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-636116.3 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | VCAM1 | ||||||
| Gene Name | vascular cell adhesion molecule 1 precursor | ||||||
| Synonyms | VCAM1 | ||||||
| Species | Bos taurus | ||||||
| Ensembl Gene | ENSBTAG00000037539 | ||||||
| Encoded Proteins |
vascular cell adhesion molecule 1
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| Protein Structure | |||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162692:
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 3:42743611-42766060 | ||||||
| Strand | Reverse strand | ||||||
| Band | |||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 380 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Interferon gamma signaling pathway
Integrin cell surface interactions pathway
Extracellular matrix organization pathway
Cytokine Signaling in Immune system pathway
Interferon Signaling pathway
Adaptive Immune System pathway
Immune System pathway
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| KEGG |
Cell adhesion molecules (CAMs) pathway
Leukocyte transendothelial migration pathway
Malaria pathway
African trypanosomiasis pathway
Cell adhesion molecules (CAMs) pathway
Leukocyte transendothelial migration pathway
Malaria pathway
African trypanosomiasis pathway
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| INOH | |||||||
| PID NCI |
Thromboxane A2 receptor signaling
Beta1 integrin cell surface interactions
Cellular roles of Anthrax toxin
Beta2 integrin cell surface interactions
Alpha9 beta1 integrin signaling events
Alpha4 beta1 integrin signaling events
a4b7 Integrin signaling
Beta5 beta6 beta7 and beta8 integrin cell surface interactions
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| Cross-References | |||||||
| SwissProt | |||||||
| TrEMBL | A7MBB0 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 534578 | ||||||
| UniGene | Bt.42912 | ||||||
| RefSeq | NM_001101158 XM_005204134 | ||||||
| HUGO | |||||||
| OMIM | |||||||
| CCDS | |||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | BC151459 DAAA02007753 | ||||||
| GenPept | AAI51460 | ||||||
| RNA Seq Atlas | 534578 | ||||||