Version 5.4
| Bos taurus Gene: PMEL17 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-636420.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | PMEL17 | ||||||||
| Gene Name | melanocyte protein PMEL precursor | ||||||||
| Synonyms | PMEL17; RPE1; SILV | ||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000004019 | ||||||||
| Encoded Proteins |
melanocyte protein Pmel 17 precursor
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185664:
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 5:57669835-57677941 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | A3F9J0 A3F9J1 F1MFK3 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 281487 | ||||||||
| UniGene | Bt.5091 | ||||||||
| RefSeq | NM_001080215 XM_005206504 XM_005206505 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02013536 EF363684 EF363685 | ||||||||
| GenPept | ABN13416 ABN13417 | ||||||||
| RNA Seq Atlas | 281487 | ||||||||