Version 5.4
Bos taurus Gene: MMP19
Summary
InnateDB Gene IDBG-636447.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MMP19
Gene Name matrix metalloproteinase-19 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009051
Encoded Proteins
IDBP-688368
matrix metalloproteinase-19
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123342:
This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:57751506-57757615
Strand Forward strand
Band
Transcripts
ENSBTAT00000011924 ENSBTAP00000011924
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005509 calcium ion binding
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0031012 extracellular matrix
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000123342
View Gene Order
ENSMUSG00000025355
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150401
Collagen degradation pathway
REACT_118779
Extracellular matrix organization pathway
REACT_118572
Degradation of the extracellular matrix pathway
REACT_206066
Extracellular matrix organization pathway
REACT_199052
Degradation of the extracellular matrix pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q08DI9 Q1H8W2
UniProt Splice Variant
Entrez Gene 533203
UniGene Bt.3681
RefSeq NM_001075983 XM_005206637
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AM260469 BC123722 DAAA02013536
GenPept AAI23723 CAJ91113
RNA Seq Atlas 533203

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca