Version 5.4
Bos taurus Gene: FBP2
Summary
InnateDB Gene IDBG-636456.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBP2
Gene Name Fructose-1,6-bisphosphatase isozyme 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019554
Encoded Proteins
IDBP-688380
Fructose-1,6-bisphosphatase isozyme 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130957:
This gene encodes a gluconeogenesis regulatory enzyme which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:82396095-82438817
Strand Reverse strand
Band
Transcripts
ENSBTAT00000026056 ENSBTAP00000026056
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity
GO:0042578 phosphoric ester hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006094 gluconeogenesis
GO:0016311 dephosphorylation
GO:0046854 phosphatidylinositol phosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030018 Z disc
GO:0030054 cell junction
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000130957
View Gene Order
ENSMUSG00000021456
View Gene Order
Pathways
NETPATH
REACTOME
REACT_221274
Metabolism of carbohydrates pathway
REACT_219973
Myoclonic epilepsy of Lafora pathway
REACT_227222
Gluconeogenesis pathway
REACT_211129
Glycogen storage diseases pathway
REACT_224672
Glucose metabolism pathway
REACT_219139
Metabolism pathway
REACT_207087
Disease pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1520
Gluconeogenesis pathway
REACT_200783
Myoclonic epilepsy of Lafora pathway
REACT_474
Metabolism of carbohydrates pathway
REACT_111217
Metabolism pathway
REACT_116125
Disease pathway
REACT_723
Glucose metabolism pathway
REACT_200833
Glycogen storage diseases pathway
REACT_189085
Disease pathway
REACT_261601
Glucose metabolism pathway
REACT_188937
Metabolism pathway
REACT_263230
Gluconeogenesis pathway
REACT_203949
Glycogen storage diseases pathway
REACT_203841
Myoclonic epilepsy of Lafora pathway
REACT_248571
Metabolism of carbohydrates pathway
KEGG
hsa00010
Glycolysis / Gluconeogenesis pathway
hsa00030
Pentose phosphate pathway pathway
hsa04910
Insulin signaling pathway pathway
hsa00051
Fructose and mannose metabolism pathway
mmu00030
Pentose phosphate pathway pathway
mmu00051
Fructose and mannose metabolism pathway
mmu04910
Insulin signaling pathway pathway
mmu00010
Glycolysis / Gluconeogenesis pathway
INOH
INOH website
Glycolysis Gluconeogenesis pathway
INOH website
Pentose phosphate cycle pathway
PID NCI
Cross-References
SwissProt Q2KJJ9
TrEMBL
UniProt Splice Variant
Entrez Gene 514066
UniGene
RefSeq NM_001046164
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102390
GenPept AAI02391
RNA Seq Atlas 514066

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca