Version 5.4
Bos taurus Gene: BT.79452
Summary
InnateDB Gene IDBG-636928.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.79452
Gene Name mitochondrial import inner membrane translocase subunit Tim17-B
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018496
Encoded Proteins
IDBP-688906
mitochondrial import inner membrane translocase subunit Tim17-B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000126768:
This gene encodes a protein that is part of the mitochondrial transport TIMM23 complex. TIM translocase complexes facilitate the transport of mitochondrial proteins from the cytosol across the mitochondrial inner membrane and into the mitochondrion. Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
This gene encodes a multipass transmembrane protein that forms an integral component of the mitochondrial translocase TIM23 complex. This complex facilitates the transport of mitochondrial proteins from the cytosol across the mitochondrial inner membrane and into the mitochondrion. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome X:92088348-92092138
Strand Reverse strand
Band
Transcripts
ENSBTAT00000024618 ENSBTAP00000024618
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Biological Process
GO:0006886 intracellular protein transport
GO:0071806 protein transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005744 mitochondrial inner membrane presequence translocase complex
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031305 integral component of mitochondrial inner membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000126768
View Gene Order
ENSMUSG00000031158
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_118595
Mitochondrial protein import pathway
REACT_17015
Metabolism of proteins pathway
REACT_247926
Metabolism of proteins pathway
REACT_199101
Mitochondrial protein import pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MS17
UniProt Splice Variant
Entrez Gene 540765
UniGene
RefSeq NM_001046488 XM_005228160
HUGO HGNC:17310
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02073075
GenPept
RNA Seq Atlas 540765

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca