InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PCDH15

Summary

InnateDB Gene

IDBG-637041.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PCDH15

Gene Name

Uncharacterized protein

Synonyms

PCDH15

Species

Bos taurus

Ensembl Gene

ENSBTAG00000045905

Encoded Proteins

IDBP-689062

protocadherin-related 15

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000150275:
This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur. [provided by RefSeq, Dec 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 26:5017714-5578654

Strand

Forward strand

Band

Transcripts

ENSBTAT00000064432

ENSBTAP00000054566

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0001964	startle response
GO:0002009	morphogenesis of an epithelium
GO:0007015	actin filament organization
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion
GO:0007601	visual perception
GO:0007605	sensory perception of sound
GO:0007626	locomotory behavior
GO:0007628	adult walking behavior
GO:0035058	nonmotile primary cilium assembly
GO:0035264	multicellular organism growth
GO:0042491	auditory receptor cell differentiation
GO:0048839	inner ear development
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
GO:0050973	detection of mechanical stimulus involved in equilibrioception
GO:0060013	righting reflex
GO:0060088	auditory receptor cell stereocilium organization

Cellular Component

GO:0001750	photoreceptor outer segment
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0032420	stereocilium

Orthologs

Species

Homo sapiens

Mus musculus

Gene ID

Gene Order

ENSG00000150275

View Gene Order

ENSMUSG00000052613

View Gene Order

Cross-References

SwissProt

TrEMBL

G3MYD4

UniProt Splice Variant

Entrez Gene

100140108

UniGene

Bt.62797

RefSeq

XM_005193355 XM_005225350

HUGO

HGNC:14674

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02058620 DAAA02058621 DAAA02058622 DAAA02058623 DAAA02058624 DAAA02058625

GenPept

RNA Seq Atlas

100140108

Transcript Frequencies

Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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