Version 5.4
Bos taurus Gene: WDR45
Summary
InnateDB Gene IDBG-637076.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDR45
Gene Name WD repeat domain phosphoinositide-interacting protein 4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002563
Encoded Proteins
IDBP-689064
WD repeat domain phosphoinositide-interacting protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196998:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:92234971-92240178
Strand Reverse strand
Band
Transcripts
ENSBTAT00000003319 ENSBTAP00000003319
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006914 autophagy
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000196998
View Gene Order
ENSMUSG00000039382
View Gene Order
Cross-References
SwissProt
TrEMBL Q0IIH0
UniProt Splice Variant
Entrez Gene 539190
UniGene Bt.4393
RefSeq NM_001076151 XM_005228156
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC122648 DAAA02073076
GenPept AAI22649
RNA Seq Atlas 539190

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca