Bos taurus Gene: GGT5
Summary
InnateDB Gene IDBG-637223.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GGT5
Gene Name gamma-glutamyltransferase 5 precursor
Synonyms GGTLA1
Species Bos taurus
Ensembl Gene ENSBTAG00000006608
Encoded Proteins
gamma-glutamyltransferase 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000099998:
This gene is a member of a gene family that encodes gamma-glutamyl transpeptidase enzymes. This enzyme consists of a heavy and a light chain, and is able to hydrolyze the gamma-glutamyl moiety of glutathione. It converts leukotriene C4 to leukotriene D4, however, it doesn't convert synthetic substrates that are commonly used to assay gamma-glutamyl transpeptidase. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
This gene is a member of a gene family that encodes gamma-glutamyl transpeptidase enzymes. This enzyme consists of a heavy and a light chain, and is able to hydrolyze the gamma-glutamyl moiety of glutathione. It converts leukotriene C4 to leukotriene D4, however, it doesn\'t convert synthetic substrates that are commonly used to assay gamma-glutamyl transpeptidase. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:73425746-73434932
Strand Reverse strand
Band
Transcripts
ENSBTAT00000023658 ENSBTAP00000023658
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003840 gamma-glutamyltransferase activity
Biological Process
GO:0006749 glutathione metabolic process
GO:0006954 inflammatory response
GO:0019370 leukotriene biosynthetic process
Cellular Component
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Synthesis of Leukotrienes (LT) and Eoxins (EX) pathway
Arachidonic acid metabolism pathway
Glutathione synthesis and recycling pathway
Glutathione conjugation pathway
Metabolism of lipids and lipoproteins pathway
Aflatoxin activation and detoxification pathway
Phase II conjugation pathway
Metabolism pathway
Biological oxidations pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Arachidonic acid metabolism pathway
Synthesis of Leukotrienes (LT) and Eoxins (EX) pathway
KEGG
Arachidonic acid metabolism pathway
Cyanoamino acid metabolism pathway
Taurine and hypotaurine metabolism pathway
Glutathione metabolism pathway
Glutathione metabolism pathway
Arachidonic acid metabolism pathway
Taurine and hypotaurine metabolism pathway
Cyanoamino acid metabolism pathway
INOH
Prostaglandin Leukotriene metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL F1MYJ3
UniProt Splice Variant
Entrez Gene 787326
UniGene Bt.24605
RefSeq NM_001191219 XM_005218272 XM_005218273
HUGO HGNC:4260
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02045686
GenPept
RNA Seq Atlas 787326