Version 5.4
Bos taurus Gene: BT.56667
Summary
InnateDB Gene IDBG-637272.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.56667
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016944
Encoded Proteins
IDBP-689270
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000128271:
This gene encodes a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. The encoded protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:73576018-73589968
Strand Reverse strand
Band
Transcripts
ENSBTAT00000029397 ENSBTAP00000029397
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001609 G-protein coupled adenosine receptor activity
GO:0004871 signal transducer activity
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0001963 synaptic transmission, dopaminergic
GO:0001973 adenosine receptor signaling pathway
GO:0001975 response to amphetamine
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007626 locomotory behavior
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0032230 positive regulation of synaptic transmission, GABAergic
GO:0042755 eating behavior
GO:0046636 negative regulation of alpha-beta T cell activation
GO:0050728 negative regulation of inflammatory response
GO:0060080 regulation of inhibitory postsynaptic membrane potential
GO:2001235 positive regulation of apoptotic signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000128271
View Gene Order
ENSMUSG00000020178
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11046
NGF-independant TRKA activation pathway
REACT_19327
G alpha (s) signalling events pathway
REACT_18288
Adenosine P1 receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_11061
Signalling by NGF pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_12056
NGF signalling via TRKA from the plasma membrane pathway
REACT_21340
GPCR ligand binding pathway
REACT_11064
Activation of TRKA receptors pathway
REACT_18342
Nucleotide-like (purinergic) receptors pathway
REACT_242871
G alpha (s) signalling events pathway
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_232333
Nucleotide-like (purinergic) receptors pathway
REACT_231468
GPCR ligand binding pathway
REACT_248921
Signalling by NGF pathway
REACT_237883
NGF signalling via TRKA from the plasma membrane pathway
REACT_188257
Signal Transduction pathway
REACT_209347
NGF-independant TRKA activation pathway
REACT_217410
Activation of TRKA receptors pathway
REACT_253800
Adenosine P1 receptors pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
hsa04020
Calcium signaling pathway pathway
hsa05012
Parkinson's disease pathway
hsa04270
Vascular smooth muscle contraction pathway
mmu04020
Calcium signaling pathway pathway
mmu04080
Neuroactive ligand-receptor interaction pathway
mmu05012
Parkinson's disease pathway
mmu04270
Vascular smooth muscle contraction pathway
INOH
INOH website
GPCR Adenosine A2A receptor signaling pathway pathway
INOH website
GPCR signaling pathway
INOH website
GPCR Adenosine A2A receptor signaling pathway pathway
INOH website
GPCR signaling pathway
PID NCI
hif2pathway
HIF-2-alpha transcription factor network
Cross-References
SwissProt
TrEMBL E1BKU0
UniProt Splice Variant
Entrez Gene 617828
UniGene Bt.56667
RefSeq XM_002694674 XM_003583354 XM_003587198 XM_005195135 XM_005195136 XM_005195137 XM_005195138 XM_005218282 XM_005218283 XM_005218284 XM_005218285 XM_870153
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02045690 DAAA02045691 DAAA02045692
GenPept
RNA Seq Atlas 617828

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca