Bos taurus Gene: SERPIND1
Summary
InnateDB Gene IDBG-637655.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERPIND1
Gene Name heparin cofactor 2 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013973
Encoded Proteins
heparin cofactor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000099937:
The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:74224243-74230708
Strand Forward strand
Band
Transcripts
ENSBTAT00000018574 ENSBTAP00000018574
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
Cellular Component
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Intrinsic Pathway pathway
Common Pathway pathway
Formation of Fibrin Clot (Clotting Cascade) pathway
Hemostasis pathway
Hemostasis pathway
Intrinsic Pathway pathway
Formation of Fibrin Clot (Clotting Cascade) pathway
Common Pathway pathway
KEGG
Complement and coagulation cascades pathway
Complement and coagulation cascades pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.91351
RefSeq NM_001105046 XM_005218199
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas