Version 5.4
Bos taurus Gene: PLSCR2
Summary
InnateDB Gene IDBG-637967.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLSCR2
Gene Name Phospholipid scramblase 2
Synonyms PLSCR2
Species Bos taurus
Ensembl Gene ENSBTAG00000022227
Encoded Proteins
IDBP-690011
Phospholipid scramblase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 22453241
[Homo sapiens] PLSCR1 regulates TLR9 trafficking to endosomal compartment and plays an important role in the induction of type I IFN response in plasmocytoid dendritic cells.
PMID 22453241
[Mus musculus] Plscr1 regulates Tlr9 trafficking to endosomal compartment and plays an important role in the induction of type I IFN response in plasmocytoid dendritic cells.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000188313:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:122911096-122937932
Strand Forward strand
Band
Transcripts
ENSBTAT00000030005 ENSBTAP00000029993
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 72 interaction(s) predicted by orthology.
Predicted by orthology
Total 72 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000188313
View Gene Order
ENSMUSG00000032369
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q3ZBG9
TrEMBL
UniProt Splice Variant
Entrez Gene 513193
UniGene Bt.96910
RefSeq NM_001034436
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103299
GenPept AAI03300
RNA Seq Atlas 513193

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca