Bos taurus Gene: CNTF | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-637978.3 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | CNTF | ||||||||||||||||||
Gene Name | Uncharacterized protein | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||
Ensembl Gene | ENSBTAG00000003624 | ||||||||||||||||||
Encoded Proteins |
ciliary neurotrophic factor
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000242689:
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 15:83291643-83293465 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | |||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Homo sapiens
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME | |||||||||||||||||||
KEGG |
Cytokine-cytokine receptor interaction pathway
Jak-STAT signaling pathway pathway
Cytokine-cytokine receptor interaction pathway
Jak-STAT signaling pathway pathway
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INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | E1BFH9 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 100848228 | ||||||||||||||||||
UniGene | |||||||||||||||||||
RefSeq | XM_003583194 XM_003587031 | ||||||||||||||||||
HUGO | HGNC:2169 | ||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | |||||||||||||||||||
HPRD | |||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | DAAA02041806 | ||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | 100848228 | ||||||||||||||||||